Osteoporosis: Definition, Risk Factors, Symptoms, And More

Osteoporosis cannot be completely cured. As a result, timely osteoporosis treatment and an early detection are the only best options for minimizing the risks associated with osteoporosis.

What Is Osteoporosis?

Osteoporosis is a reduction in bone density that causes fragile bones. This can lead to having weak bones that are prone to fractures. Osteoporosis patients tend to develop abnormally porous bones that are more compressible. The skeleton disorder can cripple bones, thus making the bones susceptible to constant bone fractures.

Risk Factors Associated With Osteoporosis:

• Genetics.
• Certain medications like corticosteroids.
• History of Rheumatoid arthritis.
• Cigarette smoking.
• Low body weight.
• Personal history of fracture as an adult.
• Excessive alcohol consumption.
• Lack of exercise, calcium, and vitamin D.

Symptoms Of Osteoporosis:

• Loss of height over-time.
• Back pain.
• Receding gums.
• Fractured bones.
• A stooped posture.
• Fragile bones.
• Bone loss in the jaw.
• Decreased grip strength.
• Weak and brittle fingernails.

Currently, there are several pharmaceutical companies trying to develop therapies for Osteoporosis. These include Celltrion, Entera Bio, Qilu Pharmaceutical, Haoma Medica, Enteris Biopharma, Teva Pharmaceuticals, Jiangsu HengRui Medicine, Radius Health, Eli Lilly and Company, Pfizer Inc, Amgen Inc, Novartis AG, and several others.

Osteoporosis Preventive Measures Include:

• Lifestyle Changes – Exercising regularly, a balanced diet that includes adequate vitamin D and calcium, quitting smoking, and curtailing excessive alcohol intake.
• Osteoporosis medications – Teriparatide (Forteo), zoledronate (Reclast), denosumab (Prolia), ibandronate (Boniva), calcitonin (Calcimar), raloxifene (Evista), risedronate (Actonel), and alendronate (Fosamax).

Most Anticipated Osteoporosis Drugs:

• NaQuinate, By Haoma Medica.
• TVB-009, By Teva Pharmaceuticals.
• HS-20090-2, By Shanghai Hansoh Biomedical.
• SHR-1222, By Jiangsu HengRui Medicine.
• EB613, By Entera Bio.
• Oral PTH Analogs, By Enteris Biopharma.
• CT-P41, By Celltrion.
• QL1206, By Qilu Pharmaceutical.

Presently, generic drugs and biosimilars flood the Osteoporosis treatment market. However, with upcoming pipeline therapies, many new treatment options can be expected to enter the Osteoporosis treatment market.

Source: Anticipated Emerging Osteoporosis Drugs to Alter Treatment Outcome, By Delveinsight.